SCIENTIFIC REFERENCES ON NIACIN, VITAMIN B3, NAD, etc.

Nicotinamide adenine dinucleotide (NAD) is a coenzyme that is found in all kinds of living cells, ranging from bacteria to man. Present both in the cytoplasm and in the nucleus. This special molecule plays an important role in the biochemical pathways that converts nutrients into energy within the mitochondria. Additionally, NAD protects tissues from free radicals (skin barrier integrity), supports innate immune function, boosts DNA repair, increases energy, and extends life span.
The human body manufactures NAD from vitamin B3 (niacin, niacinamide) delivered in our diet, but the majority of the NAD in the body (total quantity of about 3 grams in the average person) is in a constant state of synthesis, degradation, and recycling.

DISCLAIMER: There are still no completed clinical trials confirming that the replenishment of the coenzyme NAD (Nicotinamide adenine dinucleotide) by any method treats, cures, or prevents any disease, including COVID-19. The human evidence only shows that NAD precursors – B3 vitamins, like Niacin or Niacinamide or Nicotinamide Riboside (NR) or Nicotinamide Mononucleotide (NMN) – are safe and effective at replenishing NAD. The effect of that replenishment in humans remains unproven. It is only in animal studies that we consistently see NAD replenishment having a positive effect on physical conditions involving NAD depletion.