The potential mild Niacin-flush can be avoided or further minimized in two ways:
- Decreasing the concentration of Nicomenthyl 20 in the formulation, down to 0.5% or even less.
- Formulating a more “anhydrous” composition, with less glycols and more oily ingredients (such as waxes), to slow down the skin penetration of menthyl nicotinate. This will extend the time-release absorption and prevent the flush effect or make it almost unperceivable, still maintining an optimal detox efficacy.